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Figure 4 | BMC Bioinformatics

Figure 4

From: caCORRECT2: Improving the accuracy and reliability of microarray data in the presence of artifacts

Figure 4

Scatter plots of gene expression after quality insult versus original gene expression. Data shown are for one representative chip, and all probe sets on the HG-U133A platform. Gene Expression is calculated either independently with MAS5.0 or with RMA as part of a batch containing the 81 independent chips in the original Hess et al. training set. caCORRECT normalization is performed independently for each chip as part of a batch with the 81 chips of the Hess et al. training set. Units of gene expression are on the scale of the natural log of probe intensity. caCORRECT improves gene estimation in all cases, as exhibited by scatter plots closer to a line with unitary slope. This figure has been reproduced with permission from [23].

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