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Table 2 Recall of different methods at different rank levels, for orphan diseases

From: ProDiGe: Prioritization Of Disease Genes with multitask machine learning from positive and unlabeled examples

 

top 1

top 10

top 1%

top 5%

top 10%

ProDiGe2

0.1

1.4

16.8

50.4

68.1

ProDiGe3-4

1.9

13.1

42.7

66.9

76.1

PRINCE

0.5

4.8

36.9

52.9

60.6

  1. In this case, since the disease has no known causal genes, only the causal genes of other diseases intervene in the learning, meaning that ProDiGe3 and 4 are equivalent approaches.
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BMC Bioinformatics

ISSN: 1471-2105

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