Skip to main content

Table 4 Prioritization with ProDiGe4 for 8 diseases with only 2 known genes

From: ProDiGe: Prioritization Of Disease Genes with multitask machine learning from positive and unlabeled examples

Disease name MIM Id Training ∩ IPA Precision (%) Recall (%) P-value
Glaucoma 606657 2 8 12.5 2.0e-11
Creutzfeld-Jacob 123400 2 2 40.0 1.3e-06
Hyperparathyroidism 145000 2 3 18.7 1.1e-06
Psoriasis 177900 2 4 6.0 1.8e-05
Glioblastoma 137800 2 16 10.7 8.4e-19
Cystic fibrosis 219700 2 5 10.6 9.3e-08
Pancreatic carcinoma 260350 1 8 9.6 2.3e-10
Thalassemia 604131 0 2 25.0 2.6e-06
  1. The results were validated by comparing our top 100 genes with a list of genes related to the disease, extracted from Ingenuity database.