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Figure 5 | BMC Bioinformatics

Figure 5

From: Techniques for analysing pattern formation in populations of stem cells and their progeny

Figure 5

Pair correlation functions: diffusive signalling. (a) PCFs for simulations with diffusive signalling. For each set of parameter values PCFs are calculated using the results of Msim = 100 realisations (corresponding to the individual realisations shown in Figure 4). The dashed line is the cross PCF g S (r) for pairs of cells of the same type whilst the solid line is the PCF g(r) for all pairs of cells. Arrows highlight r p , the point of intersection of g S and g, which is a quantitative estimate of pattern size. (b) Distribution of the values of rp calculated from each individual realisation of the simulation with Sdiff = 10 and λ = 1,5,10,40 (error bars show mean plus or minus one standard deviation). Only realisations in which the maximum value of g S - g is greater than 0.02 (ignoring those realisations in which all cells differentiate to the same type) are included; for λ = 1, 5,10,40 this corresponds to n = 43, 78, 96,100 of 100 realisations, respectively.

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