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Table 3 Semantic roles

From: The BioLexicon: a large-scale terminological resource for biomedical text mining

Role Name Description Example ([...] = semantic argument, small capitals = focussed verb)
AGENT Drives/instigates event [The narL gene product] ACTIVATES the nitrate reductase operon
THEME a) Affected by/results from event
b) Focus of events describing states
[recA protein] was INDUCED by UV radiation
MANNER Method/way in which event is carried out cpxA gene INCREASES the levels of csgA transcription by [dephosphorylation] of CpxR
INSTRUMENT Used to carry out event EnvZ FUNCTIONS through [OmpR] to control NP porin gene expression in E. Coli.
LOCATION Where complete event takes place Phosphorylation of OmpR MODULATES expression of the ompF and ompC genes in [Escherichia coli]
SOURCE Start point of event A transducing lambda phage was ISOLATED from [a strain] harboring a glpD''lacZ fusion
DESTINATION End point of event Transcription is activated by BINDING of the cyclic AMP (cAMP)-cAMP receptor protein (CRP) complex to [a CRP binding site]
TEMPORAL Situates event in time/w.r.t. another event The Alp protease activity is DETECTED in cells [after introduction] of plasmids
CONDITION Environmental conditions/changes in conditions Strains carrying a mutation in the crp structural gene fail to REPRESS ODC and ADC activities in response to [increased cAMP]
RATE Change of level or rate marR mutations ELEVATED inaA expression by [10- to 20-fold] over that of the wild-type.
DESCRIPTIVE-AGENT Descriptive information about AGENT of event HyfR ACTS as [a formate-dependent regulator]
DESCRIPTIVE-THEME Descriptive information about THEME of event The FNR protein RESEMBLES [CRP].
PURPOSE Purpose/reason for the event occurring The fusion strains were USED [to study] the regulation of the cysB gene
  1. For each semantic role, a brief description is given, together with an example sentence containing an instance of the role. In the example sentences, the verb on which the event is centred is indicated using small capitals, whilst the event argument corresponding to the appropriate semantic role is indicated within square brackets.