Dual channel rank-based intensity weighting for quantitative co-localization of microscopy images

BMC Bioinformatics

Table 1 Effect of random noise on Manders and RWC co-localization coefficients

	Noise SD 5		Noise SD 10		Noise SD 15
FIGURE	Co-loc A on B	Co-loc B on A	Co-loc A on B	Co-loc B on A	Co-loc A on B	Co-loc B on A
4A	M₁ = 1.0	M₂ = 1.0	M₁ = 0.99	M₂ = 0.99	M₁ = 0.99	M₂ = 0.99
	RWC₁ = 0.98	RWC₂ = 0.98	RWC₁ = 0.95	RWC₂ = 0.95	RWC₁ = 0.92	RWC₂ = 0.92
4B	M₁ = 0.90	M₂ = 0.83	M₁ = 0.88	M₂ = 0.84	M₁ = 0.89	M₂ = 0.85
	RWC₁ = 0.62	RWC₂ = 0.61	RWC₁ = 0.62	RWC₂ = 0.61	RWC₁ = 0.61	RWC₂ = 0.61
4C	M₁ = 0.76	M₂ = 0.76	M₁ = 0.76	M₂ = 0.76	M₁ = 0.77	M₂ = 0.77
	RWC₁ = 0.5	RWC₂ = 0.5	RWC₁ = 0.49	RWC₂ = 0.49	RWC₁ = 0.49	RWC₂ = 0.49
4D	M₁ = 0.83	M₂ = 0.90	M₁ = 0.84	M₂ = 0.88	M₁ = 0.85	M₂ = 0.89
	RWC₁ = 0.61	RWC₂ = 0.62	RWC₁ = 0.61	RWC₂ = 0.62	RWC₁ = 0.61	RWC₂ = 0.61

ISSN: 1471-2105