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Table 4 Comparison of the transformation methods

From: Impact of the spotted microarray preprocessing method on fold-change compression and variance stability

 

Edwards + Log2

Edwards + glog

Edwards + hybrid

TRUE POSITIVES

585

643

698

TRUE NEGATIVES

636

630

597

FALSE POSITIVES

81

87

120

FALSE NEGATIVES

410

352

297

SENSITIVITY

0.588

0.646

0.702

SPECIFICITY

0.887

0.879

0.833

CLASSIFICATION ACCURACY

0.713

0.744

0.756

  1. Number of true positives, true negatives, false positives and false negatives generated by microarray data with an Edwards background correction method combined with three transformations methods.