Figure 8

THP-1 clustering of undifferentiated and differentiated structures. Hierarchical clustering (Ward's method) of one-thousand structures from four parallel MCMC5C runs, two on the undifferentiated THP-1 dataset and two on the differentiated THP-1 dataset (250 structures each). The colors along the top indicate which state each structure originated from (undifferentiated run one = blue, run two = red; differentiated run one = pink, run two = orange) and demonstrate a clear distinction between the two states, indicating that the undifferentiated and differentiated cell states specify different structure signatures.