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Table 1 Features of functional annotations described by AIGO metrics

From: AIGO: Towards a unified framework for the Analysis and the Inter-comparison of GO functional annotations

Measure Feature of a functional annotation
Coverage Proportion of genes annotated by a FA
Richness Proportion of GO terms used by a FA
Nb. of annotations Number of annotations of a given gene
Coherence Similarity of the terms in a set of annotations
Compactness Similarity of the annotation sets in a FA
Specificity Specificity of the annotations for a given gene
Information Content Informativeness of the annotations for a given gene
Redundancy Proportion of redundant terms in a set of annotations
Obsolescence Proportion of obsolete terms in a FA
Semantic similarity Degree of functional relatedness between two annotation sets
Hierarchical Precision Proportion of the annotations in a given FA being also found in a gold-standard
Hierarchical Recall Proportion of the annotations in the gold-standard being also found in a given FA
  1. The different metrics computed by AIGO allow describing particular features of functional annotations.