Table 1 Features of functional annotations described by AIGO metrics
Measure | Feature of a functional annotation |
|---|---|
Coverage | Proportion of genes annotated by a FA |
Richness | Proportion of GO terms used by a FA |
Nb. of annotations | Number of annotations of a given gene |
Coherence | Similarity of the terms in a set of annotations |
Compactness | Similarity of the annotation sets in a FA |
Specificity | Specificity of the annotations for a given gene |
Information Content | Informativeness of the annotations for a given gene |
Redundancy | Proportion of redundant terms in a set of annotations |
Obsolescence | Proportion of obsolete terms in a FA |
Semantic similarity | Degree of functional relatedness between two annotation sets |
Hierarchical Precision | Proportion of the annotations in a given FA being also found in a gold-standard |
Hierarchical Recall | Proportion of the annotations in the gold-standard being also found in a given FA |