Table 2 Comparison of Estimates for Local FDR (100 simulations).
From: Analyzing 2D gel images using a two-component empirical bayes model
50 bins, N= 550 | 100 bins, N= 550 | 100 bins, N= 5500 | |||||
|---|---|---|---|---|---|---|---|
z | unconstrained | constrained | unconstrained | constrained | unconstrained | constrained | |
2 | ratio | 1.42 | 1.04 | 3.80 | 1.20 | 1.17 | 1.00 |
relative SD | 0.24 | 0.05 | 0.40 | ||||
2.5 | ratio | 1.99 | 1.17 | 1.25 | 1.30 | 1.30 | 1.00 |
relative SD | 0.23 | 0.02 | 0.25 | ||||
3 | ratio | 3.16 | 1.14 | 62.0 | 1.30 | 1.48 | 0.95 |
relative SD | 0.14 | 0.003 | 0.15 | ||||
3.5 | ratio | 8.98 | 1.17 | 535.6 | 1.30 | 1.94 | 0.97 |
relative SD | 0.04 | 0.0004 | 0.10 | ||||
4 | ratio | 35.9 | 1.34 | 764.6 | 1.60 | 2.81 | 1.00 |
relative SD | 0.01 | 0.00004 | 0.06 | ||||