Table 3 Five most significant genes identified by CDEP as related to common metastatic mechanism across different cancer types by using FDR < 0.05 as threshold
Up-regulated genes | Down-regulated genes |
|---|---|
Glycoprotein (transmembrane) nmb (GPNMB) | Serpin peptidase inhibitor, clade B (ovalbumin), member 5 (SERPINB5) |
Secreted phosphoprotein 1 (SPP1) | proteasome (prosome, macropain) subunit, beta type, 9 (PSMB9) |
Transforming growth factor, beta-induced (TGFBI) | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (MX1) |
Heat shock 27kDa protein 1 (HSPB1) | interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) |
Mesoderm specific transcript homolog (MEST) | ubiquitin D (UBD) |