Meta-analytic approach to the accurate prediction of secreted virulence effectors in gram-negative bacteria

BMC Bioinformatics

Table 3 Putative novel effectors of serovar Typhimurium predicted by the system

Rank	STM-ID	Name	Description	PSOTb 3.0	Ref. ^#	Poodle-S
3	STM1087	pipA	pathogenicity island encoded protein: SPI3	Cytoplasmic	[10]	13
4	STM1055	gtgE	Gifsy-2 prophage	Unknown	[6]	17
32	STM3155		putative cytoplasmic protein	Unknown	[6]	18
40	STM1239		putative cytoplasmic protein	Cytoplasmic	-	11
41	STM2534		putative cytoplasmic protein	Cytoplasmic	-	12
42	STM2007		putative TPR repeat protein	Extracellular	[2]	7
43	STM1670		putative serine/threonine protein kinase	Unknown	[1, 2, 6]	16
44	STM3278		putative cytoplasmic protein	Unknown	[3]	9
45	STM2761		putative inner membrane protein	Cytoplasmic	[3]	10
46	STM4504		putative cytoplasmic protein	Cytoplasmic	[2]	3
47	STM0335		putative outer membrane protein	Unknown	-	4
48	STM2139	steD	putative inner membrane protein	Unknown	[2, 5]	24
49	STM2779		putative inner membrane protein	Unknown	-	21
50	STM1554		putative coiled-coil protein	Unknown	[1]	13
51	STM4302		putative cytoplasmic protein	Unknown	[3]	15
52	STM1939		putative glucose-6-phosphate dehydrogenase	Unknown	[1, 2]	13
53	STM3052		putative outer membrane protein	Unknown	[1]	8
54	STM2879	sicP	chaparone, related to virulence	Cytoplasmic	-	9
55	STM0497		putative periplasmic protein	Unknown	-	10
56	STM2585	steE	Gifsy-1 prophage: similar to transpose	Unknown	[1]	12
57	STM2008		putative periplasmic protein	Unknown	[1, 2]	8
58	STM2893	invI	Surface presentation of antigens; secretory proteins	Cytoplasmic	[1–3, 6]	10
59	STM1669		Homology to invasin C of Yersinia; intimin	OuterMembrane	[1, 6]	9
60	STM1940		putative cell wall-associated hydrolase	Unknown	-	14

#---References for virulence annotation from the high throughput experiments. The list of references is described in Additional file 9 'Supp_Table_VirlenceAnnot.xls'.

ISSN: 1471-2105