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Table 1 General schema for a pathway enrichment test

From: Integrative set enrichment testing for multiple omics platforms

 

Differential gene (D)

Non-differential gene (D')

Total

In the set (S)

g SD

g SD'

g S

Not in the set (S')

g S'D

g S'D'

g S'

Total

g D

g D'

g

  1. The general scheme for a hypergeometric test of differential genes is based on g genes divided by the criteria of inclusion in the set of interest (S) and inclusion in the set of differential genes (D).