Work and data flow of openBIS for Next Generation Sequencing. Integration of openBIS in the workflow of a Next Generation Sequencing core facility. Users can access openBIS through the openBIS webclient to enter new samples, track sample state and to download result data. Facility personnel registers samples after delivery and use openBIS to organize the workflow and to add processing quality control and metadata to the corresponding samples. Sequencing data undergoes real time analysis and the processed data is stored and connected to the samples metadata. Users receive a notification once the sequence data is ready for download.