Table 1 Comparison of performances of different methods on simple models of pure epistatic interactions
From: SNPInterForest: A new method for detecting epistatic interactions
| Â | SNPInterForest | BOOST | SNPHarvester | |||
|---|---|---|---|---|---|---|
| Â | # of true positives (N total = 50) | # of false positives | # of true positives (N total = 50) | # of false positives | # of true positives (N total = 50) | # of false positives |
h2 = 0.4, MAF = 0.2 | 50 | 0 | 50 | 6 | 37 | 0 |
h2 = 0.4, MAF = 0.4 | 50 | 0 | 50 | 9 | 38 | 0 |
h2 = 0.3, MAF = 0.2 | 50 | 0 | 50 | 1 | 36 | 0 |
h2 = 0.3, MAF = 0.4 | 50 | 0 | 50 | 5 | 38 | 0 |
h2 = 0.2, MAF = 0.2 | 49 | 1 | 50 | 1 | 36 | 0 |
h2 = 0.2, MAF = 0.4 | 49 | 0 | 50 | 5 | 39 | 1 |
| Â | # of true positives (Ntotal = 5) | # of false positives | # of true positives (Ntotal = 5) | # of false positives | # of true positives (Ntotal = 5) | # of false positives |
3SNP interaction | 5 | 0 | - | - | 0 | 0 |