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Table 3 Change of ranking when using the modified Gumbel distribution

From: Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling

  FQPS λ2 = 0 FQPS λ2 ≠ 0
Query rank Subject L S p-value rank Subject L S p-value
P08100 433 Q90456 287 1.1 × 10 -21 445 Q8N6U8 529 7.2 × 10 -29
L Q = 348 476 Q8N6U8 529 2.1 × 10 -21 483 Q90456 287 2.1 × 10 -28
P50052 79 P32250 308 1.1 × 10 -37 64 P34975 380 1.2 × 10 -57
L Q = 363 100 P34975 380 1.8 × 10 -37 111 P32250 308 1.3 × 10 -56
Q18179 772 P18901 446 2.2 × 10 -21 790 P79291 228 9.2 × 10 -27
L Q = 455 837 P79291 228 1.1 × 10 -20 794 P18901 446 9.8 × 10 -27
P35348 825 Q8HYN8 297 9.8 × 10 -24 826 O70432 167 5.2 × 10 -30
L Q = 466 937 O70432 167 1.3 × 10 -21 847 Q8HYN8 297 1.9 × 10 -29
  1. Examples of blast hits for the four proteins used for FQPS. The original result sets have been re-ranked according the the FQPS statistics. Left column: Gumbel assumption (λ2 = 0). Right column: Modified Gumbel distribution (λ2 ≠ 0).
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BMC Bioinformatics

ISSN: 1471-2105

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