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Table 10 TC scores for different weights of secondary structures on the SABmark benchmark. Bold denotes the two best scores, and an extra superscript of star denotes the highest score.

From: MSACompro: protein multiple sequence alignment using predicted secondary structure, solvent accessibility, and residue-residue contacts

w2 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1
TC 39.948 42.643 45.262 47.442 48.754 49.005 * 48.745 48.352 47.142 45.4923 43.385
  1. The results show that using secondary structure information (i.e. w2 > 0) always increases the alignment scores over without using it (i.e. w2 = 0). MSACompro yielded the highest accuracy score of ~68.70 when w2 is set to 0.5.