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Table 2 Total TC scores on the full-length BAliBASE 3.0 subsets.

From: MSACompro: protein multiple sequence alignment using predicted secondary structure, solvent accessibility, and residue-residue contacts

MSA tools

RV11

RV12

RV20

RV30

RV40

RV50

MSACompro

47.13

86.93

47.16

58.63

64.42

63.43

Clustalw

22.74

71.30

21.98

25.63

39.55

30.75

DIALIGN-TX

26.53

75.23

30.49

36.83

44.82

46.56

FSA

26.95

81.77

18.68

24.63

47.43

39.81

MAFFT

28.05

74.36

32.85

41.07

47.51

49.31

MSAProbs

44.11

86.5

46.44

57.63

62.18

60.75

MUSCLE

31.79

80.39

35

38.6

45.02

45.94

Opal

41.97

84.05

34.61

42.03

51.35

50.06

POA

15.26

63.84

23.34

26.73

33.67

27

Probalign

45.34

86.20

43.93

53.6

60.31

54.94

ProbCons

41.66

85.55

40.63

51.47

53.22

57.31

T-coffee

42.29

85.25

38.88

47

55.94

58.69

  1. Bold denotes the highest scores. MSACompro yielded the highest TC scores on all the subsets.