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Table 4 Overall mean SP and TC scores on the SABmark 1.65.

From: MSACompro: protein multiple sequence alignment using predicted secondary structure, solvent accessibility, and residue-residue contacts

MSA tools Mean SP score Mean TC score
MSACompro 68.85 49.07
Clustalw 52.18 31.17
DIALIGN-TX 50.49 29.66
FSA 46.03 25.73
MAFFT 51.99 31.72
MSAProbs 60.55 39.95
MUSCLE 54.99 34.35
Opal 58.28 37.84
POA 38.28 19.02
Probalign 59.96 38.66
ProbCons 59.81 38.99
T-coffee 59.49 39.08
  1. Bold denotes the highest scores. The improvement of SP and TC scores on this data set is substantial.