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Table 2 Top 10 selected covariates for preclustered GO-groups according to 100 splits into training and test data

From: Survival models with preclustered gene groups as covariates

count GO effect medoid clustersize annotation
85 GO:0043170 -1 209258_s_at 410 macromolecule metabolic process
81 GO:0007049 -1 210052_s_at 222 cell cycle
74 GO:0050896 +1 211908_x_at 102 response to stimulus
52 GO:0032501 +1 212195_at 310 multicellular organismal process
40 GO:0032501 +1 210935_s_at 362 multicellular organismal process
21 GO:0050794 +1 210417_s_at 312 regulation of cellular process
18 GO:0043170 -1 211693_at 434 macromolecule metabolic process
18 GO:0050896 +1 204118_at 230 response to stimulus
16 GO:0006952 +1 203535_at 27 defense response
15 GO:0042221 -1 219140_s_at 39 response to chemical stimulus
  1. Names are GenBank IDs for the medoid genes and GO IDs for GO groups [7]. The first column corresponds to the selected number for the covariate across 100 splits into training and test data for L 1 regression on the Mainz cohort study. The value of the effect indicates whether the covariate has an increasing(+1) or decreasing (- 1) effect on patients' risk to die.