Figure 3

The side-chains positioning problem. We compare 10 models constructed for target T0295 with the native structure of T0295, available in the PDB as file 2H1R (shown in red). We show only the backbones of each model and the native structure, except for the sidechain of Tyr64. The diversity observed for the conformation of this sidechain emphasizes the difficulty to model sidechains accurately.