A quality metric for homology modeling: the H-factor

BMC Bioinformatics

Table 4 H-factor applied to NMR structures with 20 models or more.

PDB id	Scoring function (a)				H-factor (%)	cRMS (Å) (b)
	*(1)*	*(2)*	*(3)*	*(4)*
1A5E	1.03	n/a	2.13	3.43	28	1.95
1A2I	1.24	n/a	1.48	3.8	34	2.29
1A24	0.74	n/a	2.27	4.5	38	2.79
1A57	1.38	n/a	2.33	4.67	35	2.91
1A5J	0.99	n/a	2.38	4.67	35	2.91
1A67	0.37	n/a	2.67	4.8	37	3.03

(a) See text for the description of the scoring functions (3) and (4); these two functions measure the structural dispersion of the models considered, as well as their similarities to homologue structures in the PDB; note that scores (1) and (2) usually present in the H-factor are meaningless for this test set.
(b) Average RMS between each model and the "mean" structure computed from all the models.

ISSN: 1471-2105