Steps in identifying subtypes from morphological descriptors of a tissue section. (A) Each patient may have multiple tissue sections, which are accessible along with the computed features and coded clinical information through BioSig in (B). (C) Each feature, from each tissue, is represented as a density distribution that is normalized in (D). (E) Subtyping identifies 5 classes through consensus voting. (F) Following the Kaplan Meier test, only one subtype proved to have a significant p-value between pair-wise survival curves.