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Figure 5 | BMC Bioinformatics

Figure 5

From: Partition decoupling for multi-gene analysis of gene expression profiling data

Figure 5

Pathway-PDM results for top pathways in radiation response data. Points are placed in the grid according to cluster assignment from layers 1 and 2 along for pathways with frand < 0.05. Exposure is indicated by shape ("M"-mock; "U"-UV; "I"-IR), with phenotypes (healthy, skin cancer, low RS, high RS) indicated by color. Several pathways (nucleotide excision repair, Parkinson's disease, and DNA replication) cluster samples by exposure in one layer and phenotype in the other, suggesting that these mechanisms differ between the case and control groups.

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