Figure 1

Sample Taxonomic Assignment of an Ambiguous Read. Assigning read R _i to the j th node of T _i partitions the leaves of T _i into true positives, false positives, true negatives, and false negatives. In this example, the hits are M _i = {s₁, s₅, s₆, s₇}. If we let j be the blue circled node, we obtain TP _i,j = {s₅, s₆, s₇}, FP _i,j = {s₈}, TN _i,j = {s₂, s₃, s₄}, FN _i,j = {s₁}. True hit H = s₅ (defined in Section "Validation: Performance in ROC Space").