Figure 2From: Network based transcription factor analysis of regenerating axolotl limbsTranscription factor connectivity in axolotl proteomics data. The five most highly connected TFs (c-Myc, SP1, HNF4A, ESR1 and p53) and their downstream targets from the bait list proteins (represented by small green circles) are shown here. The size of the TF circle corresponds to its connectivity; a bigger circle entails higher overall connectivity. The targets in the outer circle are unique targets of each TF while those in the inner circle are shared by two or more TFs.Back to article page