Table 3 Indirect Functional Analysis

miRNA

Target Gene

Terms

miRNA

Target Gene

Terms

hsa-miR-9

BACE1

Endoplasmic reticulum, Golgi apparatus, integral to membrane, Gol, gi apparatus, Aspartyl protease

hsa-miR-422b

-

hsa-miR-363*

-

hsa-miR-23a

CXCL12

CELL ADHESION, CHEMOTAXIS, POSITIVE REGULATION OF MONOCYTE CHEMOTAXIS, EXTRACELLULAR SPACE

hsa-miR-20b*

ARID4B

TRANSCRIPTION REGULATION, NUCLEUS

hsa-miR-193a

-

MYLIP

PROTEIN UBIQUITINATION, UBIQUITIN-PROTEIN LIGASE ACTIVITY, NERVOUS SYSTEM DEVELOPMENT

hsa-miR-155

AGTR1

REGULATION OF NATRIURESIS, REGULATION OF CELL GROWTH, POSITIVE REGULATION OF INFLAMMATORY RESPONSE, REGULATION OF BLOOD VESSEL SIZE BY RENIN-ANGIOTENSIN

HIPK3

TRANSCRIPTION REGULATION, NUCLEUS

LDOC1

negative regulation of cell proliferation

CDKN1A

negative regulation of cell proliferation, response to toxin, response to UV, positive regulation of programmed cell death, cyclin-dependent protein kinase inhibitor activity

MATR3

nuclear matrix, RNA binding, protein binding

hsa-miR-19a*

PTEN

induction of apoptosis, regulation of cyclin-dependent protein kinase activity

BACH1

Transcription regulation, Nucleus, transcription factor activity

hsa-miR-17-5p*

E2F1

TRANSCRIPTION REGULATION, NUCLEUS, TRANSCRIPTION FACTOR ACTIVITY

TM6SF1

MEMBRANE

NCOA3

POSITIVE REGULATION OF TRANSCRIPTION, DNA-DEPENDENT, NUCLEUS, HISTONE ACETYLTRANSFERASE ACTIVITY

TP53INP1

INDUCTION OF APOPTOSIS

hsa-miR-17-3p*

-

-

hsa-miR-130b

-

-