Table 3 Completely novel P. falciparum dPUC predictions lead to refined protein annotations
From: Using context to improve protein domain identification
Protein ID | Standard Pfam domains | Additional dPUC domains | Current annotation (PlasmoDB 6.0) | Suggested reannotation (this study) |
|---|---|---|---|---|
PFL0980w | CwfJ_C_1 | CwfJ_C_2 | conserved Plasmodium protein, unknown function | Debranching enzyme-associated ribonuclease (DRN1 ortholog), putative |
PF13_0222 | Metallophos | DBR1 | phosphatase, putative | RNA lariat debranching enzyme (DBR1 ortholog), putative |
PF11_0086 | MIF4G | PAM2 | MIF4G domain containing protein | Poly(A)-binding protein-interacting protein 1 (PAIP1 ortholog), putative |
PFE1390w | DEAD, Helicase_C | zf-CCHC | RNA helicase-1 | Post-translational mRNA regulation (ABSTRAKT ortholog), putative |
PF08_0130 | WD40 | Utp13 | WD-repeat protein, putative | U3 ribonucleoprotein component (PWP2 ortholog), putative |
PF14_0456 | WD40 | Utp12 | conserved Plasmodium protein, unknown function | U3 ribonucleoprotein component (DIP2 ortholog), putative |
PF10_0128 | WD40 | Utp13 | WD-repeat protein, putative | U3 ribonucleoprotein component (UTP13 ortholog), putative |
PFI1025w | RRM_1 | Lsm_interact | RNA binding protein, putative | U4/U6 snRNA-associated-splicing factor (PRP24 ortholog), putative |
PFL0985c | DUF367 | RLI | conserved protein, unknown function | Ribosome biogenesis regulator (TSR3 ortholog), putative |
MAL8P1.19 | DEAD, Helicase_C | DBP10CT | RNA helicase, putative | Ribosomal biogenesis RNA helicase protein (DBP10 ortholog), putative |
PFE0560c | MORN | Avl9 | MORN repeat protein, putative | Atypical Golgi transport protein (AVL9 ortholog) with MORN domains, putative |
PFL1455w | DUF202, SPX | VTC | conserved Plasmodium protein, unknown function | Vacuolar transporter chaperone (VTC2/3/4 ortholog), putative |
PFL2255w | TPR_2 | F-box | conserved Plasmodium protein, unknown function | DNA replication origin binding protein (DIA2 ortholog), putative |
PFF1070c | UPF0004, Radical_SAM | TRAM | radical SAM protein, putative | Ribosome or tRNA methylthiotransferase (RIMO or MIAB ortholog) or CDK5 regulatory subunit-associated protein 1, putative |
PFL1045w | DUF814 | FbpA | conserved protein, unknown function | FbpA domain protein, putative |
MAL13P1.182 | RanBPM_CRA | LisH | conserved Plasmodium protein, unknown function | GID8 ortholog, putative |
MAL13P1.79 | zf-CCCH, WD40 | conserved Plasmodium protein, unknown function | CCCH zinc finger protein, putative | |
MAL13P1.37 | zf-B_box | conserved Plasmodium protein, unknown function | Tripartite motif protein, putative |