Table 1 Comparison of GSEA approaches

1

BioCarta;Erythropoietin mediated neuroprotection through NF-kB

BioCarta;Erythropoietin mediated neuroprotection through NF-kB

2

SuperArray;Homeobox (HOX) Genes

BioCarta;Induction of apoptosis through DR3 and DR4/5 Death Receptors

3

BioCarta;The IGF-1 Receptor and Longevity

BioCarta;Roles of -arrestin-dependent Recruitment of Src Kinases in GPCR Signaling

4

BioCarta;Induction of apoptosis through DR3 and DR4/5 Death Receptors

SuperArray;Homeobox (HOX) Genes

5

BioCarta;IL12 and Stat4 Dependent Signaling Pathway in Th1 Development

BioCarta;HIV-I Nef negative effector of Fas and TNF

6

BioCarta;HIV-I Nef negative effector of Fas and TNF

TCA Cycle;Metabolic Process

7

BioCarta;Roles of -arrestin-dependent Recruitment of Src Kinases in GPCR Signaling

hsa00310;Lysine degradation

8

TCA Cycle;Metabolic Process

hsa03018;RNA degradation

9

hsa00310;Lysine degradation

hsa05014;Amyotrophic lateral sclerosis (ALS)

10

hsa03018;RNA degradation

SuperArray;Stress/Toxicity PathwayFinder

Rank

GSEA - limma

sigPathway

1

B Cell Receptor Signaling Pathway;Cellular Process

BioCarta;Caspase Cascade in Apoptosis

2

hsa03018;RNA degradation

KEGG:03050;Proteasome

3

SuperArray;G-Proteins/Signaling Molecules

KEGG:04130;SNARE interactions in vesicular transport

4

TNF-alpha/NF-kB Signaling Pathway;Cellular Process

SuperArray;Heat Shock Proteins

5

hsa00510;N-Glycan biosynthesis

Proteasome Degradation;Physiological Process

6

hsa04142;Lysosome

KEGG:00380;Tryptophan metabolism

7

SuperArray;Autophagy

BioCarta;FAS signaling pathway (CD95)

8

BioCarta;Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia

KEGG:04612;Antigen processing and presentation

9

Translation Factors;Cellular Process

KEGG:03020;RNA polymerase

10

BioCyc;glyoxylate cycle II

KEGG:00020;Citrate cycle (TCA cycle)