SNP-based pathway enrichment analysis for genome-wide association studies

BMC Bioinformatics

Table 1 Eight significant pathways (P <= 0.001) discovered in both European-American ancestry and African-American ancestry data sets of schizophrenia

PATHWAYS		European Ancestry (EA)			African Ancestry (AA)
		Nom P	GENE SIZE	SNP SIZE	Nom P	GENE SIZE	SNP SIZE
HSA04720	Long-term potentiation	<0.001	67	135	0.001	67	66
HSA04270	Vascular smooth muscle contraction	<0.001	107	215	<0.001	107	105
HSA05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	<0.001	72	144	<0.001	72	135
HSA04020	Calcium signaling pathway	<0.001	168	337	<0.001	174	165
HSA04360	Axon guidance	<0.001	122	245	<0.001	126	120
HSA04080	Neuroactive ligand-receptor interaction	<0.001	256	509	<0.001	266	248
HSA04510	Focal adhesion	<0.001	186	378	<0.001	191	186
HSA04730	Long-term depression	< 0.001	68	134	0.001	68	129

ISSN: 1471-2105