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Figure 3 | BMC Bioinformatics

Figure 3

From: An efficient algorithmic approach for mass spectrometry-based disulfide connectivity determination using multi-ion analysis

Figure 3

Two-stage matching spectra for protein ST8SiaIV. (A) In the first-stage (DMS vs. PMS), the theoretical disulfide-bonded structure is matched with the doubly charged precursor ion with highest intensity, whose m/z = 1082.9. (B) For this initial match, the disulfide-bonded peptide pair is fragmented and the fragments are matched with the MS/MS spectrum for the precursor ion (FMS vs. TMS), generating a list of validation matches.

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