Figure 7
From: A genetic algorithm-based boolean delay model of intracellular signal transduction in inflammation
Logical gates to biological processes. Boolean network include combinations of logic operator (AND, OR, NOT) were developed from the knowledge of components directly upstream of each target node in the network. The logic gate also called transfer function which modified with information from the literature. We use OR operator when either of upstream nodes could activate the target component. AND operator is for synergy, which means two or more upstream nodes are necessary to activate the target component. In the other case, the NOT operator represents inhibition or competition.