Compound | IC50 nM | Errora | Fit valueb | Activity scalec | ||
---|---|---|---|---|---|---|
Experimental | Estimated | Experimental | Estimated | Â | Â | Â |
1 | 4 | 1.7 | -2.4 | 9.52 | ++++ | ++++ |
2 | 7 | 16 | +2.3 | 8.54 | ++++ | ++++ |
3 | 13 | 13 | -1 | 8.64 | ++++ | ++++ |
4 | 52 | 88 | +1.7 | 7.80 | ++++ | ++++ |
5 | 90 | 150 | +1.7 | 7.57 | ++++ | +++ |
6 | 115 | 170 | +1.5 | 7.51 | +++ | +++ |
7 | 240 | 190 | -1.3 | 7.48 | +++ | +++ |
8 | 348 | 320 | -1.1 | 7.24 | +++ | +++ |
9 | 450 | 470 | +1.1 | 7.07 | +++ | +++ |
10 | 674 | 460 | -1.5 | 7.08 | +++ | +++ |
11 | 730 | 610 | -1.2 | 6.97 | +++ | +++ |
12 | 980 | 1400 | +1.4 | 6.60 | +++ | ++ |
13 | 1500 | 880 | -1.7 | 6.80 | ++ | + |
14 | 2800 | 8100 | +2.9 | 5.84 | ++ | ++ |
15 | 4600 | 5200 | +1.1 | 6.03 | ++ | ++ |
16 | 8000 | 10000 | +1.3 | 5.73 | ++ | ++ |
17 | 12000 | 8000 | -1.6 | 5.84 | + | ++ |
18 | 19000 | 19000 | -1 | 5.48 | + | + |
19 | 25000 | 6100 | -4.1 | 5.96 | + | ++ |
20 | 37000 | 38000 | +1 | 5.16 | + | + |