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Table 2 Clustering results obtained from docking of withaferin A into Hsp90/Cdc37 complex

From: Hsp90/Cdc37 Chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug Withaferin A

Receptor

No. of AutoDockclustersa, b

Cluster rankb

No. of structuresin the cluster

Lowest binding energy of cluster

Energy range within cluster

  

1

3

-13.95

-13.95 to -10.18

Hsp90/Cdc37 complex

2 (10)

2

7

-13.58

-13.58 to -10.11

  1. a Number of GA runs are shown in parentheses
  2. b Clustering is done with RMS tolerance of 5.0 Ã…