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Figure 1 | BMC Bioinformatics

Figure 1

From: Interaction site prediction by structural similarity to neighboring clusters in protein-protein interaction networks

Figure 1

Outline of the proposed method. ‘T’ in red is a target protein and ‘A’ – ‘J’ indicate its neighboring proteins that are extracted from the PPI network, where the neighboring proteins are defined as proteins within a distance of two from the target protein in the PPI network. Interaction sites are predicted by extracting a pocket whose shape and physical properties are commonly observed among ‘A’ – ‘J’ and ‘T’.

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BMC Bioinformatics

ISSN: 1471-2105

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