Predictive results of density-based linear regression model. (A)-(C) Average correlation coefficient of 10-fold CV in three gene sets. (D) Comparative analysis of two models using ESC-specific gene subsets that co-bound by pluripotent TF pairs. Red solid circles are the cases that the density profiles of a TF pair are significantly different. (E) Distinct binding profiles in two gene classes that are either well explained (C1) or inefficiently explained (C2). (F) Contribution of each TF and epigenetic effects in density-based regression models (Methy: DNA methylation, HistM: histone mark, CpGI: CpG Island).