Example of regulatory network of TF interactions with epigenetic effects. This network was generated by the connectivity of nodes in all interaction terms. For example, an interaction term A:B:C is split into three interactions, A:B, A:C, and B:C. Then, the nodes are linked to each other and to the target gene set. A pairwise interaction with an epigenetic effect is treated differently. For example, in the case of B:Methy, B is not linked to the target gene set.