Table 1 Analysis of factors and their value sets of hypothesis and the results of statistical test (by Fisher’s exact test ) for the TMA data stored in Xperanto-RDF
Hypothesis | Shared property among samples | Classifier | Dependent property | Number of samples (cores) /slides/experiments found in Xperanto-RDF | P value |
|---|---|---|---|---|---|
Reduced expression of Apaf-1 in colorectal carcinoma correlates with high-grade phenotype [10]. | Colon cancer | Apaf-1 intensity (0 vs. 1-3) | Grade (High vs. Low-grade) | 55/5/3 | < 0.0001 |
In gastric cancer, Apaf-1 expression is associated with high grade malignancy. | Stomach caner | Apaf-1 intensity (0 vs. 1-3) | Grade (High vs. Low-grade) | 52/4/3 | < 0.0001 |
In colon cancer, the expression of Leptin is associated with negative lymph node metastasis [19]. | Colon cancer | Leptin (positive vs. negative) | Nodal status (N0 vs N1-N3) | 52/4/3 | < 0.0001 |
In gastric cancer patients, HDAC2 expression was associated with negative lymph node metastasis [20]. | Stomach caner | HDAC2 expression (positive vs. negative) | Nodal status (N0 vs N1-N3) | 50/3/2 | < 0.0001 |