Table 1 Five topics with highly populated BW drugs (>70%)
From: Mining FDA drug labels using an unsupervised learning technique - topic modeling
Topics | Statistics | Corresponding ADRs from MedDRA | |||
|---|---|---|---|---|---|
# drugs | # BW Drugs | % | P-value | ||
Topic 5 | 21 | 15 | 71% | 0.0121 | Creatinine; renal-failure; hyperkalemia; potassium; injury |
Topic 6 | 20 | 16 | 80% | 0.0014 | Suicide; irritability; restlessness; agitation; anxiety |
Topic 8 | 19 | 14 | 74% | 0.01 | Bleeding; stroke; gastrointestinal-bleeding; myocardial-infarction; coronary artery bypass |
Topic 18 | 14 | 13 | 93% | 2.38E-4 | Death; psychosis; elderly; dementia; extrapyramidal symptoms |
Topic 24 | 11 | 9 | 82% | 0.0135 | Hepatitis; hepatotoxicity; hepatic-failure; injury; death |