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Table 2 Five topics with highly populated drugs (>70%) in a therapeutic category

From: Mining FDA drug labels using an unsupervised learning technique - topic modeling

Topics Statistics Corresponding ADRs from MedDRA
  # drugs Therapeutic categories (First Level of ATC) % P-value  
Topic 1 31 Antineoplastic and immunomodulating agents (L/24) 81% 0.0005 Neutropenia; stomatitis; infection; myelosuppression; sepsis; immunosuppression
Topic 4 21 Antiinfectives for systemic use (J/19) 96% 0.0005 Colitis; diarrhea; allergy; colectomy; eosinophilia
Topic 6 20 Nervous system (N/14) 73% 0.0011 Suicide; irritability; restlessness; agitation; anxiety
Topic 18 14 Nervous system (N/11) 88% 8.31E-004 Death; psychosis; elderly; dementia; extrapyramidal symptoms
Topic 22 12 Nervous system (N/8) 75% 0.020 Depression; excitement; dysphoria; unconsciousness; sleep disturbances