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Figure 2 | BMC Bioinformatics

Figure 2

From: Latent Semantic Indexing of PubMed abstracts for identification of transcription factor candidates from microarray derived gene sets

Figure 2

Workflow for the LSI based TF ranking for microarray derived gene sets. Microarray data was analyzed to identify differentially expressed genes (DEGs) in response to treatments. A list of 433 mouse TFs was derived from the TRANSFAC database and a significance test was conducted to identify TFs showing high average literature association with the entire set of DEGs relative to the entire gene population of 21,027 genes. TFs were ranked according to the literature-derived enrichment p-values.

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BMC Bioinformatics

ISSN: 1471-2105

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