Latent Semantic Indexing of PubMed abstracts for identification of transcription factor candidates from microarray derived gene sets

Table 2 CORE_TF motif ranking for five microarray derived gene sets.

	Core_TF Results
	# motifs (p-value = 0)	Avg # TFs per motif	Total # of TFs
Interferon stimulated genes	86	2.55	125
IL-4 stimulated genes	10	1.60	16
Tunicamycin stimulated genes	5	1.20	6
Growth Hormone (GH) stimulated genes	27	2.26	40
TGF-β1 stimulated genes	7	2.29	10

Multiple TF motifs were ranked first (p-value=0) for the various gene sets. Also, each TF motif was mapped to multiple TFs, making it difficult to prioritize critical TFs for each gene set.

ISSN: 1471-2105