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Table 5 Top 25 ranked TFs for five microarray derived gene sets using the abstract cooccurrence model.

From: Latent Semantic Indexing of PubMed abstracts for identification of transcription factor candidates from microarray derived gene sets

abstract co-occurrrence model

Rank

Interferon

IL-4

Tunicamycin

GH

TGF-β1

1

Irf1

Hif1a

Ddit3

Nfkb1

Hif1a

2

Stat1

Sfpi1

Egr1

Stat1

Egr1

3

Irf9

Tcfap2a

Gfi1

Cebpb

Runx2

4

Stat6

Irf1

Ppara

Rel

Smad3

5

Stat4

Rela

Ppard

Foxp3

Sp1

6

Nr3c1

Egr1

Tcfap2a

Kitl

Smad4

7

Irf3

Pparg

Tcf3

Nfatc2

Smad1

8

Sfpi1

Nfkb1

Rara

Rela

Tcf3

9

Myc

Stat1

Zbtb16

Irf1

Nkx2-5

10

Jund

Ikzf1

Rarg

Stat6

Tcf4

11

Atf3

Foxo1

Cebpd

Jun

Elk3

12

Ifi47

Gata1

Hoxa9

Sfpi1

Tcfap2a

13

Prdm1

Itgal

Rxra

Cebpd

Tcf12

14

Stat3

Kitl

Hsf1

Ddit3

Smad7

15

Foxn1

Foxn1

Nr5a1

Foxn1

Zbtb16

16

Ep300

Fosl1

Pparg

Irf3

Bcl6

17

Usf1

Stat6

Otx1

Ep300

Pgr

18

Irf8

Stat3

Ep300

Vdr

Cebpd

19

Bcl6

Fos

Jund

Cebpa

Ep300

20

Rxrb

Jun

Srebf1

Fos

Smad2

21

Hsf1

Nfatc2

Hand1

E2f1

Jun

22

Rela

Foxp3

Hif1a

Sp1

Foxo3

23

Junb

Sp1

Egr2

Ppara

Pax5

24

Fos

Foxo3

Runx2

Myb

Ppara

25

Stat2

Pxn

Gata3

Pax5

Myod1

  1. Ddit3 (in bold font) was the only ground truth TF ranked by this method. The ground truth TFs were chosen because they were targeted in the published study as critical regulators for each gene set.