Table 3 Top ten modules with significant biological enrichment in KEGG
From: Constructing a robust protein-protein interaction network by integrating multiple public databases
Cluster ID | KEGG Pathway | Total number of proteins in the module | Number of proteins in the KEGG Pathway from the module | Total number of proteins in the KEGG Pathway | Fisher’s p-value |
|---|---|---|---|---|---|
1 | RNA polymerase / Transcription / Genetic Information Processing | 10 | 10 | 29 | 5.10E-24 |
2 | Progesterone-mediated oocyte maturation / Endocrine System / Cellular Processes | 12 | 12 | 86 | 1.91E-22 |
3 | Proteasome / Folding_ Sorting and Degradation / Genetic Information Processing | 17 | 12 | 48 | 5.22E-22 |
4 | Basal transcription factors / Transcription / Genetic Information Processing | 9 | 9 | 36 | 1.24E-20 |
5 | Cell cycle / Cell Growth and Death / Cellular Processes | 12 | 12 | 128 | 2.97E-20 |
6 | Ubiquitin mediated proteolysis / Folding_ Sorting and Degradation / Genetic Information Processing | 12 | 12 | 138 | 7.61E-20 |
7 | Cell cycle / Cell Growth and Death / Cellular Processes | 13 | 12 | 128 | 3.78E-19 |
8 | Pyrimidine metabolism / Nucleotide Metabolism / Metabolism | 10 | 10 | 98 | 3.57E-18 |
9 | Oocyte meiosis / Cell Growth and Death / Cellular Processes | 12 | 11 | 114 | 4.09E-18 |
10 | RNA degradation / Folding_ Sorting and Degradation / Genetic Information Processing | 11 | 9 | 59 | 8.97E-17 |