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Table 1 Core genes of the TCA cycle and glycolysis

From: Analysis of cancer metabolism with high-throughput technologies

Gene name Gene ID mRNA accession number Pathway Copy Number of Transcript
     UHRR HBRR
CS
(Citrate synthase)
1431 NM_004077 TCA cycle 11.2 7.4
ACO2
(Aconitase 2)
50 NM_001098 TCA cycle 7.8 20.7
IDH2
(isocitrate dehydrogenase 2)
3418 NM_002168 TCA cycle 13.1 6.2
OGDH
(oxoglutarate dehydrogenase)
4967 NM_001165036 TCA cycle 2.8 3.3
SUCLA2
(succinate-CoA ligase)
8803 NM_003850 TCA cycle 1.1 2.1
SDHA
(succinate dehydrogenase complex, sub. A)
6389 NM_004168 TCA cycle 20.5 15.4
FH
(fumarate hydratase)
2271 NM_000143 TCA cycle 6.5 2.8
MDH1
(malate dehydrogenase 1)
4190 NM_005917 TCA cycle 10.4 26.2
HK1
(hexokinase 1)
3098 NM_033500 Glycolysis 2.3 3.0
GPI
(glucose-6-phosphate isomerase)
2821 NM_000175 Glycolysis 11.9 10.3
PFKL
(phosphofructokinase, liver)
5211 NM_002626 Glycolysis 21.7 10.3
ALDOA
(aldolase A, fructose-bisphosphate)
226 NM_000034 Glycolysis 49.9 25.0
TPI1
(triosephosphate isomerase 1)
7167 NM_001159287 Glycolysis 68.4 29.8
GAPDH
(glyceraldehyde-3-phosphate dehydrogenase)
2597 NM_002046 Glycolysis 886.6 287.3
PGK1
(phosphoglycerate kinase 1)
5230 NM_000291 Glycolysis 67.4 15.1
PGAM1
(phosphoglycerate mutase 1)
5223 NM_002629 Glycolysis 41.5 27.6
ENO1
(enolase 1)
2023 NM_001428 Glycolysis 264.2 51.3
PKM2
(pyruvate kinase)
5315 NM_002654 Glycolysis 37.7 21.3