Figure 2

Rgyr distribution of the initial conformational ensemble before filtration. Conformers shown in the graph are some examples in the initial conformational ensemble of LRP6 intracellular domain. The number below each conformer is the value of its radius of gyration. A conformer with a smaller value of radius of gyration has a compact conformation (the structure on the left). A conformer with a larger value of radius of gyration has an extended conformation (the structure on the right). Two conformers with a mean value of radius of gyration are shown in the middle.