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Table 3 End-to-end distance simulation results for LRP6 intracellular domain.

From: Near-membrane ensemble elongation in the proline-rich LRP6 intracellular domain may explain the mysterious initiation of the Wnt signaling pathway

  Length Motifs contained start-end ∆mean (Constraint1) ∆mean (Constraint2)
      δ=20 δ=10 δ=5
D1 103aa S/T cluster; Motif 1 24-126 12.7220 17.5067 21.9135 24.2415
D2 103aa Motif 1&2 64-166 0.8405 1.9484 2.4047 2.7648
D3 103aa Motif 1,2&3 106-208 -1.3586 -2.7764 -2.8862 -3.0856
D4 103aa Motif 2,3&4 124-226 -1.6533 -3.5066 -3.4477 -3.5721
D5 103aa Motif 2,3,4 &5 141-243 -1.4545 -3.1360 -3.1388 -3.3186
  1. The table shows the length, motif contained, starting and ending positions in LRP6 simulation sequence, and the differences between the average Rgyr of structural ensembles after each constraint and the initial structural ensemble.