The relationship between protein complexes in metabolic system. (a) We plot several highly monochromatic between-complex clusters in metabolic system. The complexes were grouped together according to their functions. The unlabeled module includes complexes associated to processes such as autophagy, trehalose biosynthesis, and ergosterol biosynthetic process. (b) The enlargement of cell cycle and DNA maintenance. Each node represents a protein complex. Green edges: positive interactions. Red edges: negative interactions. Each edge is labeled with its β. The edge size is proportional to the mean of the genetic interactions.