Gene symbol | Disease(s) or essential gene* | Gene function(s) | Sum of ranks** |
---|---|---|---|
UBC | S | • ubiquitin C | 7 |
ACTB | S | • actin, beta | 15 |
UBB | S | • ubiquitin B | 29 |
APP | E | • amyloid beta (A4) precursor protein | 32 |
FOS | S | • v-fos FBJ murine osteosarcoma viral oncogene homolog | 51 |
HSPA4 | S | • heat shock 70kDa protein 4 | 54 |
PARK2 | SD | • Parkinson disease (autosomal recessive, juvenile) 2, parkin | 67 |
SYK | B | • spleen tyrosine kinase | 97 |
TUBB2A | E | • tubulin, beta 2A | 117 |
TSC2 | S | • tuberous sclerosis 2 | 127 |
UCHL1 | E | • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 217 |
MARK3 | S | • MAP/microtubule affinity-regulating kinase 3 | 236 |
RPS27A | S | • ribosomal protein S27a pseudogene 12; ribosomal | 355 |
DNM1 | E | • dynamin 1 | 476 |
IRS2 | E | • insulin receptor substrate 2 | 497 |
GNAI2 | S | • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 519 |
SMARCC2 | B | • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 525 |
HRAS | S | • v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 527 |
SAT1 | S | • spermidine/spermine N1-acetyltransferase 1 | 529 |
CRKL | B | • v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 531 |