Table 1 Parameters used in simulation data

Reference genome

Human chromosome 22 (Build 37 ref)

Distribution of SV length

N(50, 5), N(80, 8), N(100, 10), N(120, 12),

N(150, 15), N(170, 17), N(200, 20), N(400, 40)

N(600, 60), N(800, 80), N (1000, 100)

N(2000, 200), N(4000, 400)

The rate of single nucleotide alterations

1/10000

The number of tandem repeat

N(40, 20) (>1)

Mean depth of coverage

5, 10, 15, 20, 40

Read lengths

50, 75, 100, 108

Distribution of template lengths

N(400, 50)